| Calexico to Sanford (Maine) | 2,511.46 mi (4,041.80 km) |
| Calexico to Sanford (North Carolina) | 2,075.52 mi (3,340.23 km) |
| Calexico to Sanger (California) | 360.75 mi (580.57 km) |
| Calexico to Santa Ana (California) | 155.97 mi (251.01 km) |
| Calexico to Santa Barbara (California) | 271.47 mi (436.89 km) |
| Calexico to Santa Clara (California) | 488.34 mi (785.91 km) |
| Calexico to Santa Clara (Oregon) | 890.58 mi (1,433.25 km) |
| Calexico to Santa Clarita (California) | 210.25 mi (338.36 km) |
| Calexico to Santa Cruz (California) | 474.76 mi (764.05 km) |
| Calexico to Santa Fe (New Mexico) | 581.05 mi (935.11 km) |
| Calexico to Santa Fe (Texas) | 1,226.63 mi (1,974.07 km) |
| Calexico to Santa Fe Springs (California) | 171.53 mi (276.05 km) |
| Calexico to Santa Maria (California) | 323.74 mi (521.01 km) |
| Calexico to Santa Monica (California) | 195.60 mi (314.78 km) |
| Calexico to Santa Paula (California) | 235.83 mi (379.52 km) |
