| Caister-on-Sea to Spello | 836.64 mi (1,346.44 km) |
| Caister-on-Sea to Spilamberto | 702.06 mi (1,129.86 km) |
| Caister-on-Sea to Spilimbergo | 672.93 mi (1,082.97 km) |
| Caister-on-Sea to Spinea | 682.33 mi (1,098.10 km) |
| Caister-on-Sea to Spoleto | 850.47 mi (1,368.70 km) |
| Caister-on-Sea to Spoltore | 908.98 mi (1,462.86 km) |
| Caister-on-Sea to Spresiano | 669.87 mi (1,078.06 km) |
| Caister-on-Sea to Squinzano | 1,140.99 mi (1,836.25 km) |
| Caister-on-Sea to Statte | 1,107.09 mi (1,781.69 km) |
| Caister-on-Sea to Stezzano | 600.93 mi (967.10 km) |
| Caister-on-Sea to Strada | 765.35 mi (1,231.72 km) |
| Caister-on-Sea to Stradella | 625.09 mi (1,005.98 km) |
| Caister-on-Sea to Striano | 1,015.56 mi (1,634.38 km) |
| Caister-on-Sea to Subiaco | 909.88 mi (1,464.31 km) |
| Caister-on-Sea to Sulmona | 926.07 mi (1,490.37 km) |
