| Cahokia to University Place (Washington) | 1,729.16 mi (2,782.82 km) |
| Cahokia to Upland (California) | 1,553.90 mi (2,500.76 km) |
| Cahokia to Upper Arlington (Ohio) | 393.19 mi (632.77 km) |
| Cahokia to Upper Grand Lagoon (Florida) | 632.71 mi (1,018.25 km) |
| Cahokia to Upper Montclair (New Jersey) | 862.57 mi (1,388.17 km) |
| Cahokia to Urbana (Illinois) | 150.40 mi (242.05 km) |
| Cahokia to Urbana (Maryland) | 691.24 mi (1,112.44 km) |
| Cahokia to Urbana (Ohio) | 359.44 mi (578.46 km) |
| Cahokia to Urbandale (Iowa) | 285.16 mi (458.92 km) |
| Cahokia to Utica (New York) | 840.60 mi (1,352.82 km) |
| Cahokia to Uvalde (Texas) | 847.71 mi (1,364.26 km) |
| Cahokia to Vacaville (California) | 1,711.16 mi (2,753.84 km) |
| Cahokia to Vadnais Heights (Minnesota) | 472.60 mi (760.58 km) |
| Cahokia to Vail (Arizona) | 1,238.69 mi (1,993.47 km) |
| Cahokia to Valdosta (Georgia) | 661.16 mi (1,064.03 km) |
