| Cahokia to Silver Firs (Washington) | 1,718.08 mi (2,764.98 km) |
| Cahokia to Silver Spring (Maryland) | 708.74 mi (1,140.61 km) |
| Cahokia to Silver Springs Shores (Florida) | 802.99 mi (1,292.28 km) |
| Cahokia to Silverdale (Washington) | 1,740.22 mi (2,800.61 km) |
| Cahokia to Silverton (Oregon) | 1,724.74 mi (2,775.70 km) |
| Cahokia to Simi Valley (California) | 1,609.29 mi (2,589.90 km) |
| Cahokia to Simpsonville (South Carolina) | 512.68 mi (825.08 km) |
| Cahokia to Sioux City (Iowa) | 424.23 mi (682.73 km) |
| Cahokia to Sioux Falls (South Dakota) | 484.13 mi (779.13 km) |
| Cahokia to Skokie (Illinois) | 272.07 mi (437.85 km) |
| Cahokia to Sleepy Hollow (New York) | 881.33 mi (1,418.37 km) |
| Cahokia to Slidell (Louisiana) | 572.28 mi (921.00 km) |
| Cahokia to Smithfield (North Carolina) | 685.06 mi (1,102.50 km) |
| Cahokia to Smithfield (Utah) | 1,161.24 mi (1,868.84 km) |
| Cahokia to Smithville (Missouri) | 242.87 mi (390.86 km) |
