| Cahokia to Scottsboro (Alabama) | 354.71 mi (570.85 km) |
| Cahokia to Scottsdale (Arizona) | 1,252.94 mi (2,016.41 km) |
| Cahokia to Scranton (Pennsylvania) | 791.98 mi (1,274.58 km) |
| Cahokia to Seabrook (Maryland) | 717.94 mi (1,155.41 km) |
| Cahokia to Seabrook (Texas) | 679.92 mi (1,094.23 km) |
| Cahokia to Seaford (New York) | 898.55 mi (1,446.08 km) |
| Cahokia to Seagoville (Texas) | 542.60 mi (873.23 km) |
| Cahokia to Seal Beach (California) | 1,584.57 mi (2,550.12 km) |
| Cahokia to Searcy (Arkansas) | 245.16 mi (394.55 km) |
| Cahokia to Seaside (California) | 1,728.86 mi (2,782.33 km) |
| Cahokia to SeaTac (Washington) | 1,720.10 mi (2,768.24 km) |
| Cahokia to Seattle (Washington) | 1,723.25 mi (2,773.30 km) |
| Cahokia to Sebastian (Florida) | 931.25 mi (1,498.70 km) |
| Cahokia to Sebring (Florida) | 916.80 mi (1,475.45 km) |
| Cahokia to Secaucus (New Jersey) | 869.20 mi (1,398.84 km) |
