| Cahokia to Enumclaw (Washington) | 1,703.21 mi (2,741.05 km) |
| Cahokia to Ephrata (Pennsylvania) | 755.13 mi (1,215.27 km) |
| Cahokia to Erie (Colorado) | 800.08 mi (1,287.61 km) |
| Cahokia to Erie (Pennsylvania) | 585.56 mi (942.37 km) |
| Cahokia to Erlanger (Kentucky) | 302.73 mi (487.20 km) |
| Cahokia to Escanaba (Michigan) | 520.78 mi (838.11 km) |
| Cahokia to Escondido (California) | 1,546.06 mi (2,488.15 km) |
| Cahokia to Española (New Mexico) | 890.01 mi (1,432.34 km) |
| Cahokia to Essex (Maryland) | 739.21 mi (1,189.64 km) |
| Cahokia to Essex Junction (Vermont) | 970.52 mi (1,561.90 km) |
| Cahokia to Estelle (Louisiana) | 602.53 mi (969.68 km) |
| Cahokia to Estero (Florida) | 969.48 mi (1,560.22 km) |
| Cahokia to Euclid (Ohio) | 503.01 mi (809.51 km) |
| Cahokia to Eufaula (Alabama) | 540.10 mi (869.21 km) |
| Cahokia to Eugene (Oregon) | 1,738.73 mi (2,798.22 km) |
