| Cadillac to Southern Pines (North Carolina) | 702.12 mi (1,129.95 km) |
| Cadillac to Southfield (Michigan) | 163.48 mi (263.10 km) |
| Cadillac to Southgate (Michigan) | 179.83 mi (289.41 km) |
| Cadillac to Southlake (Texas) | 1,003.05 mi (1,614.25 km) |
| Cadillac to Spanaway (Washington) | 1,780.61 mi (2,865.61 km) |
| Cadillac to Spanish Fork (Utah) | 1,366.61 mi (2,199.34 km) |
| Cadillac to Spanish Lake (Missouri) | 451.25 mi (726.22 km) |
| Cadillac to Spanish Springs (Nevada) | 1,775.11 mi (2,856.76 km) |
| Cadillac to Sparks (Nevada) | 1,779.54 mi (2,863.89 km) |
| Cadillac to Spartanburg (South Carolina) | 669.07 mi (1,076.77 km) |
| Cadillac to Spearfish (South Dakota) | 906.97 mi (1,459.63 km) |
| Cadillac to Speedway (Indiana) | 310.79 mi (500.17 km) |
| Cadillac to Spencer (Iowa) | 492.02 mi (791.84 km) |
| Cadillac to Spokane (Washington) | 1,544.56 mi (2,485.73 km) |
| Cadillac to Spokane Valley (Washington) | 1,535.36 mi (2,470.92 km) |
