| Buffalo to St. George (Utah) | 1,867.88 mi (3,006.06 km) |
| Buffalo to St. Helens (Oregon) | 2,153.24 mi (3,465.31 km) |
| Buffalo to St. James (New York) | 324.63 mi (522.43 km) |
| Buffalo to St. John (Indiana) | 452.59 mi (728.38 km) |
| Buffalo to St. Joseph (Missouri) | 855.18 mi (1,376.28 km) |
| Buffalo to St. Louis (Missouri) | 664.44 mi (1,069.31 km) |
| Buffalo to St. Louis Park (Minnesota) | 735.04 mi (1,182.94 km) |
| Buffalo to St. Marys (Georgia) | 852.42 mi (1,371.84 km) |
| Buffalo to St. Marys (Pennsylvania) | 101.09 mi (162.69 km) |
| Buffalo to St. Matthews (Kentucky) | 479.58 mi (771.81 km) |
| Buffalo to St. Michael (Minnesota) | 752.86 mi (1,211.61 km) |
| Buffalo to St. Paul (Minnesota) | 722.35 mi (1,162.50 km) |
| Buffalo to St. Peter (Minnesota) | 761.49 mi (1,225.50 km) |
| Buffalo to St. Peters (Missouri) | 676.46 mi (1,088.65 km) |
| Buffalo to St. Petersburg (Florida) | 1,065.52 mi (1,714.79 km) |
