| Buffalo to Somersworth (New Hampshire) | 402.46 mi (647.70 km) |
| Buffalo to Somerton (Arizona) | 2,065.33 mi (3,323.82 km) |
| Buffalo to Somerville (Massachusetts) | 395.17 mi (635.96 km) |
| Buffalo to Somerville (New Jersey) | 271.50 mi (436.94 km) |
| Buffalo to Sonoma (California) | 2,284.22 mi (3,676.10 km) |
| Buffalo to Soquel (California) | 2,293.39 mi (3,690.86 km) |
| Buffalo to South Bend (Indiana) | 388.49 mi (625.21 km) |
| Buffalo to South Bradenton (Florida) | 1,087.16 mi (1,749.62 km) |
| Buffalo to South Burlington (Vermont) | 301.12 mi (484.60 km) |
| Buffalo to South Charleston (West Virginia) | 348.99 mi (561.65 km) |
| Buffalo to South Daytona (Florida) | 956.60 mi (1,539.50 km) |
| Buffalo to South El Monte (California) | 2,185.09 mi (3,516.57 km) |
| Buffalo to South Elgin (Illinois) | 486.38 mi (782.76 km) |
| Buffalo to South Euclid (Ohio) | 166.76 mi (268.37 km) |
| Buffalo to South Farmingdale (New York) | 316.38 mi (509.17 km) |
