| Buffalo to Shoreview (Minnesota) | 724.98 mi (1,166.74 km) |
| Buffalo to Shorewood (Illinois) | 488.50 mi (786.17 km) |
| Buffalo to Shorewood (Wisconsin) | 456.68 mi (734.96 km) |
| Buffalo to Short Hills (New Jersey) | 276.56 mi (445.09 km) |
| Buffalo to Short Pump (Virginia) | 368.25 mi (592.64 km) |
| Buffalo to Show Low (Arizona) | 1,774.91 mi (2,856.44 km) |
| Buffalo to Shreveport (Louisiana) | 1,086.90 mi (1,749.20 km) |
| Buffalo to Sicklerville (New Jersey) | 295.88 mi (476.18 km) |
| Buffalo to Sidney (Ohio) | 328.68 mi (528.95 km) |
| Buffalo to Sierra Madre (California) | 2,181.33 mi (3,510.52 km) |
| Buffalo to Sierra Vista (Arizona) | 1,885.57 mi (3,034.52 km) |
| Buffalo to Sierra Vista Southeast (Arizona) | 1,884.92 mi (3,033.48 km) |
| Buffalo to Signal Hill (California) | 2,199.18 mi (3,539.24 km) |
| Buffalo to Sikeston (Missouri) | 703.97 mi (1,132.93 km) |
| Buffalo to Siloam Springs (Arkansas) | 953.64 mi (1,534.73 km) |
