| Buffalo to Shelton (Connecticut) | 312.72 mi (503.28 km) |
| Buffalo to Shelton (Washington) | 2,151.36 mi (3,462.28 km) |
| Buffalo to Shenandoah (Louisiana) | 1,092.86 mi (1,758.79 km) |
| Buffalo to Shepherdsville (Kentucky) | 495.06 mi (796.73 km) |
| Buffalo to Sheridan (Wyoming) | 1,400.01 mi (2,253.09 km) |
| Buffalo to Sherman (Texas) | 1,153.95 mi (1,857.10 km) |
| Buffalo to Sherrelwood (Colorado) | 1,366.80 mi (2,199.64 km) |
| Buffalo to Sherwood (Arkansas) | 906.64 mi (1,459.09 km) |
| Buffalo to Sherwood (Oregon) | 2,161.10 mi (3,477.95 km) |
| Buffalo to Shiloh (Illinois) | 652.01 mi (1,049.30 km) |
| Buffalo to Shiloh (Ohio) | 351.15 mi (565.12 km) |
| Buffalo to Shiloh (Pennsylvania) | 228.66 mi (367.99 km) |
| Buffalo to Shirley (New York) | 340.12 mi (547.37 km) |
| Buffalo to Shively (Kentucky) | 488.95 mi (786.88 km) |
| Buffalo to Shoreline (Washington) | 2,110.64 mi (3,396.75 km) |
