| Buffalo to San Luis Obispo (California) | 2,279.38 mi (3,668.30 km) |
| Buffalo to San Marcos (California) | 2,171.30 mi (3,494.37 km) |
| Buffalo to San Marcos (Texas) | 1,385.96 mi (2,230.49 km) |
| Buffalo to San Marino (California) | 2,186.00 mi (3,518.03 km) |
| Buffalo to San Mateo (California) | 2,296.44 mi (3,695.76 km) |
| Buffalo to San Pablo (California) | 2,286.94 mi (3,680.47 km) |
| Buffalo to San Rafael (California) | 2,295.23 mi (3,693.82 km) |
| Buffalo to San Ramon (California) | 2,271.85 mi (3,656.19 km) |
| Buffalo to San Tan Valley (Arizona) | 1,888.26 mi (3,038.86 km) |
| Buffalo to Sand Springs (Oklahoma) | 1,030.15 mi (1,657.86 km) |
| Buffalo to Sandusky (Ohio) | 221.43 mi (356.36 km) |
| Buffalo to Sandy (Oregon) | 2,133.30 mi (3,433.21 km) |
| Buffalo to Sandy (Utah) | 1,698.18 mi (2,732.96 km) |
| Buffalo to Sandy Springs (Georgia) | 687.38 mi (1,106.23 km) |
| Buffalo to Sanford (Florida) | 984.40 mi (1,584.24 km) |
