| Buffalo to San Diego (California) | 2,179.04 mi (3,506.83 km) |
| Buffalo to San Diego Country Estates (California) | 2,156.08 mi (3,469.88 km) |
| Buffalo to San Dimas (California) | 2,171.09 mi (3,494.03 km) |
| Buffalo to San Fernando (California) | 2,196.99 mi (3,535.71 km) |
| Buffalo to San Francisco (California) | 2,297.62 mi (3,697.66 km) |
| Buffalo to San Gabriel (California) | 2,186.17 mi (3,518.31 km) |
| Buffalo to San Germán (Puerto Rico) | 1,848.80 mi (2,975.36 km) |
| Buffalo to San Jacinto (California) | 2,139.96 mi (3,443.93 km) |
| Buffalo to San Jose (California) | 2,279.91 mi (3,669.17 km) |
| Buffalo to San Juan (Puerto Rico) | 1,850.72 mi (2,978.45 km) |
| Buffalo to San Juan (Texas) | 1,586.03 mi (2,552.47 km) |
| Buffalo to San Juan Capistrano (California) | 2,183.22 mi (3,513.56 km) |
| Buffalo to San Leandro (California) | 2,284.57 mi (3,676.67 km) |
| Buffalo to San Lorenzo (California) | 2,284.15 mi (3,675.98 km) |
| Buffalo to San Luis (Arizona) | 2,069.67 mi (3,330.80 km) |
