| Buffalo to Salisbury (New York) | 310.30 mi (499.38 km) |
| Buffalo to Salisbury (North Carolina) | 507.58 mi (816.87 km) |
| Buffalo to Salmon Creek (Washington) | 2,147.89 mi (3,456.69 km) |
| Buffalo to Salt Lake City (Utah) | 1,698.25 mi (2,733.07 km) |
| Buffalo to Sammamish (Washington) | 2,098.11 mi (3,376.59 km) |
| Buffalo to San Angelo (Texas) | 1,422.06 mi (2,288.58 km) |
| Buffalo to San Anselmo (California) | 2,297.86 mi (3,698.04 km) |
| Buffalo to San Antonio (Texas) | 1,430.91 mi (2,302.82 km) |
| Buffalo to San Benito (Texas) | 1,569.92 mi (2,526.54 km) |
| Buffalo to San Bernardino (California) | 2,144.00 mi (3,450.43 km) |
| Buffalo to San Bruno (California) | 2,300.45 mi (3,702.21 km) |
| Buffalo to San Buenaventura (California) | 2,237.67 mi (3,601.19 km) |
| Buffalo to San Carlos (California) | 2,295.67 mi (3,694.52 km) |
| Buffalo to San Carlos Park (Florida) | 1,147.15 mi (1,846.16 km) |
| Buffalo to San Clemente (California) | 2,182.69 mi (3,512.70 km) |
