| Buffalo to Saddlebrooke (Arizona) | 1,876.13 mi (3,019.34 km) |
| Buffalo to Safety Harbor (Florida) | 1,051.28 mi (1,691.87 km) |
| Buffalo to Saginaw (Michigan) | 259.54 mi (417.70 km) |
| Buffalo to Saginaw (Texas) | 1,220.55 mi (1,964.28 km) |
| Buffalo to Sahuarita (Arizona) | 1,903.65 mi (3,063.63 km) |
| Buffalo to Saks (Alabama) | 739.23 mi (1,189.68 km) |
| Buffalo to Salem (Massachusetts) | 404.20 mi (650.50 km) |
| Buffalo to Salem (Ohio) | 172.09 mi (276.95 km) |
| Buffalo to Salem (Oregon) | 2,175.96 mi (3,501.88 km) |
| Buffalo to Salem (Virginia) | 393.18 mi (632.77 km) |
| Buffalo to Salem Lakes (Wisconsin) | 471.60 mi (758.97 km) |
| Buffalo to Salida (California) | 2,230.37 mi (3,589.43 km) |
| Buffalo to Salina (Kansas) | 1,018.06 mi (1,638.40 km) |
| Buffalo to Salinas (California) | 2,286.15 mi (3,679.20 km) |
| Buffalo to Salisbury (Maryland) | 356.37 mi (573.53 km) |
