| Buffalo to Reidsville (North Carolina) | 455.65 mi (733.30 km) |
| Buffalo to Reisterstown (Maryland) | 260.58 mi (419.36 km) |
| Buffalo to Rendon (Texas) | 1,227.60 mi (1,975.64 km) |
| Buffalo to Reno (Nevada) | 2,122.00 mi (3,415.02 km) |
| Buffalo to Renton (Washington) | 2,106.17 mi (3,389.56 km) |
| Buffalo to Republic (Missouri) | 867.01 mi (1,395.32 km) |
| Buffalo to Reston (Virginia) | 284.09 mi (457.20 km) |
| Buffalo to Revere (Massachusetts) | 399.84 mi (643.48 km) |
| Buffalo to Rexburg (Idaho) | 1,645.08 mi (2,647.50 km) |
| Buffalo to Reynoldsburg (Ohio) | 288.25 mi (463.89 km) |
| Buffalo to Rialto (California) | 2,149.57 mi (3,459.40 km) |
| Buffalo to Richardson (Texas) | 1,186.76 mi (1,909.91 km) |
| Buffalo to Richfield (Minnesota) | 730.54 mi (1,175.70 km) |
| Buffalo to Richfield (Wisconsin) | 474.40 mi (763.48 km) |
| Buffalo to Richland (Washington) | 1,981.87 mi (3,189.52 km) |
