| Buffalo to Odessa (Texas) | 1,490.21 mi (2,398.27 km) |
| Buffalo to Ogden (Utah) | 1,691.79 mi (2,722.67 km) |
| Buffalo to Oildale (California) | 2,191.52 mi (3,526.91 km) |
| Buffalo to Ojus (Florida) | 1,173.16 mi (1,888.02 km) |
| Buffalo to Okemos (Michigan) | 282.37 mi (454.43 km) |
| Buffalo to Oklahoma City (Oklahoma) | 1,120.40 mi (1,803.11 km) |
| Buffalo to Okmulgee (Oklahoma) | 1,044.16 mi (1,680.42 km) |
| Buffalo to Olathe (Kansas) | 877.55 mi (1,412.28 km) |
| Buffalo to Old Jamestown (Missouri) | 659.39 mi (1,061.19 km) |
| Buffalo to Oldsmar (Florida) | 1,048.09 mi (1,686.73 km) |
| Buffalo to Olean (New York) | 60.49 mi (97.36 km) |
| Buffalo to Olive Branch (Mississippi) | 805.22 mi (1,295.87 km) |
| Buffalo to Olivehurst (California) | 2,218.91 mi (3,570.99 km) |
| Buffalo to Olney (Maryland) | 275.49 mi (443.36 km) |
| Buffalo to Olympia (Washington) | 2,143.16 mi (3,449.08 km) |
