| Buffalo to Medford (New York) | 334.06 mi (537.61 km) |
| Buffalo to Medford (Oregon) | 2,211.75 mi (3,559.46 km) |
| Buffalo to Medina (Ohio) | 197.29 mi (317.51 km) |
| Buffalo to Medulla (Florida) | 1,047.37 mi (1,685.59 km) |
| Buffalo to Mehlville (Missouri) | 672.36 mi (1,082.06 km) |
| Buffalo to Melbourne (Florida) | 1,027.12 mi (1,652.99 km) |
| Buffalo to Melissa (Texas) | 1,165.89 mi (1,876.32 km) |
| Buffalo to Melrose (Massachusetts) | 396.73 mi (638.48 km) |
| Buffalo to Melrose Park (Illinois) | 464.86 mi (748.12 km) |
| Buffalo to Melville (New York) | 315.90 mi (508.39 km) |
| Buffalo to Melvindale (Michigan) | 224.35 mi (361.05 km) |
| Buffalo to Memphis (Florida) | 1,081.34 mi (1,740.24 km) |
| Buffalo to Memphis (Tennessee) | 802.60 mi (1,291.66 km) |
| Buffalo to Menasha (Wisconsin) | 487.78 mi (785.00 km) |
| Buffalo to Mendota (California) | 2,220.89 mi (3,574.18 km) |
