| Buffalo to Lowell (Indiana) | 453.05 mi (729.11 km) |
| Buffalo to Lowell (Massachusetts) | 382.07 mi (614.89 km) |
| Buffalo to Lower Burrell (Pennsylvania) | 166.39 mi (267.77 km) |
| Buffalo to Lowes Island (Virginia) | 277.52 mi (446.63 km) |
| Buffalo to Lubbock (Texas) | 1,400.54 mi (2,253.96 km) |
| Buffalo to Lufkin (Texas) | 1,181.85 mi (1,902.00 km) |
| Buffalo to Luling (Louisiana) | 1,100.48 mi (1,771.05 km) |
| Buffalo to Lumberton (North Carolina) | 571.52 mi (919.77 km) |
| Buffalo to Lumberton (Texas) | 1,216.62 mi (1,957.96 km) |
| Buffalo to Lutz (Florida) | 1,039.57 mi (1,673.02 km) |
| Buffalo to Lynbrook (New York) | 308.33 mi (496.20 km) |
| Buffalo to Lynchburg (Virginia) | 380.55 mi (612.43 km) |
| Buffalo to Lynden (Washington) | 2,106.71 mi (3,390.43 km) |
| Buffalo to Lyndhurst (Ohio) | 165.68 mi (266.64 km) |
| Buffalo to Lyndon (Kentucky) | 476.95 mi (767.57 km) |
