| Buffalo to Iselin (New Jersey) | 283.75 mi (456.65 km) |
| Buffalo to Isla Vista (California) | 2,265.12 mi (3,645.36 km) |
| Buffalo to Issaquah (Washington) | 2,098.88 mi (3,377.83 km) |
| Buffalo to Ithaca (New York) | 123.27 mi (198.38 km) |
| Buffalo to Ives Estates (Florida) | 1,172.77 mi (1,887.39 km) |
| Buffalo to Jackson (Michigan) | 286.24 mi (460.66 km) |
| Buffalo to Jackson (Mississippi) | 958.30 mi (1,542.23 km) |
| Buffalo to Jackson (Missouri) | 685.59 mi (1,103.35 km) |
| Buffalo to Jackson (Tennessee) | 731.20 mi (1,176.75 km) |
| Buffalo to Jackson (Wyoming) | 1,598.92 mi (2,573.22 km) |
| Buffalo to Jacksonville (Alabama) | 730.62 mi (1,175.82 km) |
| Buffalo to Jacksonville (Arkansas) | 902.19 mi (1,451.94 km) |
| Buffalo to Jacksonville (Florida) | 882.35 mi (1,420.01 km) |
| Buffalo to Jacksonville (Illinois) | 629.45 mi (1,013.00 km) |
| Buffalo to Jacksonville (North Carolina) | 570.07 mi (917.44 km) |
