| Buffalo to Firestone (Colorado) | 1,357.74 mi (2,185.07 km) |
| Buffalo to Fish Hawk (Florida) | 1,056.82 mi (1,700.79 km) |
| Buffalo to Fishers (Indiana) | 420.84 mi (677.28 km) |
| Buffalo to Fitchburg (Massachusetts) | 357.40 mi (575.17 km) |
| Buffalo to Fitchburg (Wisconsin) | 534.63 mi (860.40 km) |
| Buffalo to Five Corners (Washington) | 2,143.93 mi (3,450.32 km) |
| Buffalo to Five Forks (South Carolina) | 587.96 mi (946.23 km) |
| Buffalo to Flagstaff (Arizona) | 1,824.46 mi (2,936.19 km) |
| Buffalo to Flat Rock (Michigan) | 232.00 mi (373.37 km) |
| Buffalo to Fleming Island (Florida) | 898.63 mi (1,446.21 km) |
| Buffalo to Flint (Michigan) | 245.00 mi (394.30 km) |
| Buffalo to Floral Park (New York) | 304.70 mi (490.37 km) |
| Buffalo to Florence (Alabama) | 731.24 mi (1,176.82 km) |
| Buffalo to Florence (Arizona) | 1,885.38 mi (3,034.23 km) |
| Buffalo to Florence (Kentucky) | 405.56 mi (652.68 km) |
