| Buffalo to Elkhorn (Wisconsin) | 491.29 mi (790.65 km) |
| Buffalo to Elko (Nevada) | 1,889.62 mi (3,041.05 km) |
| Buffalo to Elkridge (Maryland) | 278.66 mi (448.47 km) |
| Buffalo to Elkton (Maryland) | 276.67 mi (445.26 km) |
| Buffalo to Ellensburg (Washington) | 2,034.07 mi (3,273.52 km) |
| Buffalo to Ellicott City (Maryland) | 271.48 mi (436.90 km) |
| Buffalo to Elmhurst (Illinois) | 468.95 mi (754.70 km) |
| Buffalo to Elmira (New York) | 117.92 mi (189.77 km) |
| Buffalo to Elmont (New York) | 305.18 mi (491.14 km) |
| Buffalo to Elmwood Park (Illinois) | 462.21 mi (743.85 km) |
| Buffalo to Elmwood Park (New Jersey) | 279.52 mi (449.84 km) |
| Buffalo to Elon (North Carolina) | 471.16 mi (758.26 km) |
| Buffalo to Eloy (Arizona) | 1,905.33 mi (3,066.33 km) |
| Buffalo to Elwood (New York) | 316.97 mi (510.11 km) |
| Buffalo to Elyria (Ohio) | 197.37 mi (317.64 km) |
