| Buffalo to El Sobrante (California) | 2,161.25 mi (3,478.20 km) |
| Buffalo to Eldersburg (Maryland) | 261.00 mi (420.04 km) |
| Buffalo to Elfers (Florida) | 1,037.61 mi (1,669.87 km) |
| Buffalo to Elgin (Illinois) | 486.32 mi (782.65 km) |
| Buffalo to Elizabeth (New Jersey) | 285.32 mi (459.17 km) |
| Buffalo to Elizabeth City (North Carolina) | 477.19 mi (767.96 km) |
| Buffalo to Elizabethton (Tennessee) | 488.02 mi (785.39 km) |
| Buffalo to Elizabethtown (Kentucky) | 515.58 mi (829.74 km) |
| Buffalo to Elizabethtown (Pennsylvania) | 222.70 mi (358.40 km) |
| Buffalo to Elk City (Oklahoma) | 1,214.71 mi (1,954.89 km) |
| Buffalo to Elk Grove (California) | 2,226.92 mi (3,583.88 km) |
| Buffalo to Elk Grove Village (Illinois) | 469.96 mi (756.33 km) |
| Buffalo to Elk Plain (Washington) | 2,118.50 mi (3,409.39 km) |
| Buffalo to Elk River (Minnesota) | 747.98 mi (1,203.76 km) |
| Buffalo to Elkhart (Indiana) | 372.94 mi (600.18 km) |
