| Buffalo to Eau Claire (Wisconsin) | 643.08 mi (1,034.94 km) |
| Buffalo to Echelon (New Jersey) | 290.49 mi (467.50 km) |
| Buffalo to Eden (North Carolina) | 444.67 mi (715.62 km) |
| Buffalo to Eden Prairie (Minnesota) | 738.97 mi (1,189.26 km) |
| Buffalo to Edgewater (Florida) | 970.32 mi (1,561.58 km) |
| Buffalo to Edgewater (New Jersey) | 288.95 mi (465.03 km) |
| Buffalo to Edgewood (Maryland) | 274.80 mi (442.25 km) |
| Buffalo to Edgewood (Washington) | 2,112.75 mi (3,400.15 km) |
| Buffalo to Edina (Minnesota) | 734.41 mi (1,181.92 km) |
| Buffalo to Edinburg (Texas) | 1,579.34 mi (2,541.70 km) |
| Buffalo to Edmond (Oklahoma) | 1,108.27 mi (1,783.60 km) |
| Buffalo to Edmonds (Washington) | 2,110.66 mi (3,396.78 km) |
| Buffalo to Edwards (Colorado) | 1,453.21 mi (2,338.72 km) |
| Buffalo to Edwardsville (Illinois) | 647.01 mi (1,041.27 km) |
| Buffalo to Effingham (Illinois) | 568.83 mi (915.44 km) |
