| Buffalo to Delhi (California) | 2,222.31 mi (3,576.46 km) |
| Buffalo to Delray Beach (Florida) | 1,138.52 mi (1,832.26 km) |
| Buffalo to Deltona (Florida) | 975.99 mi (1,570.70 km) |
| Buffalo to Deming (New Mexico) | 1,733.48 mi (2,789.76 km) |
| Buffalo to Denison (Texas) | 1,146.05 mi (1,844.38 km) |
| Buffalo to Dent (Ohio) | 396.59 mi (638.25 km) |
| Buffalo to Denton (Texas) | 1,195.07 mi (1,923.27 km) |
| Buffalo to Dentsville (South Carolina) | 620.33 mi (998.32 km) |
| Buffalo to Denver (Colorado) | 1,362.04 mi (2,192.00 km) |
| Buffalo to Depew (New York) | 7.34 mi (11.81 km) |
| Buffalo to Derby (Connecticut) | 314.83 mi (506.66 km) |
| Buffalo to Derby (Kansas) | 1,036.12 mi (1,667.48 km) |
| Buffalo to Des Moines (Iowa) | 759.70 mi (1,222.62 km) |
| Buffalo to Des Moines (Washington) | 2,112.72 mi (3,400.09 km) |
| Buffalo to Des Plaines (Illinois) | 465.00 mi (748.35 km) |
