| Buffalo to Caño Martin Peña (Puerto Rico) | 1,848.88 mi (2,975.48 km) |
| Buffalo to Cañon City (Colorado) | 1,409.68 mi (2,268.66 km) |
| Buffalo to Canóvanas (Puerto Rico) | 1,856.40 mi (2,987.58 km) |
| Buffalo to Canton (Georgia) | 670.76 mi (1,079.49 km) |
| Buffalo to Canton (Illinois) | 598.76 mi (963.61 km) |
| Buffalo to Canton (Mississippi) | 936.41 mi (1,507.01 km) |
| Buffalo to Canton (Ohio) | 194.24 mi (312.60 km) |
| Buffalo to Canyon (Texas) | 1,349.12 mi (2,171.20 km) |
| Buffalo to Canyon Lake (California) | 2,157.19 mi (3,471.66 km) |
| Buffalo to Canyon Lake (Texas) | 1,399.50 mi (2,252.27 km) |
| Buffalo to Cape Coral (Florida) | 1,137.16 mi (1,830.09 km) |
| Buffalo to Cape Girardeau (Missouri) | 684.42 mi (1,101.47 km) |
| Buffalo to Carbondale (Illinois) | 652.60 mi (1,050.26 km) |
| Buffalo to Carlisle (Pennsylvania) | 205.14 mi (330.13 km) |
| Buffalo to Carlsbad (California) | 2,177.15 mi (3,503.79 km) |
