| Brussels to Southern Pines (North Carolina) | 4,131.71 mi (6,649.34 km) |
| Brussels to Southfield (Michigan) | 3,945.80 mi (6,350.15 km) |
| Brussels to Southgate (Michigan) | 3,956.10 mi (6,366.73 km) |
| Brussels to Southlake (Texas) | 4,944.88 mi (7,958.01 km) |
| Brussels to Spanaway (Washington) | 4,967.67 mi (7,994.69 km) |
| Brussels to Spanish Fork (Utah) | 5,062.06 mi (8,146.59 km) |
| Brussels to Spanish Lake (Missouri) | 4,385.41 mi (7,057.63 km) |
| Brussels to Spanish Springs (Nevada) | 5,328.47 mi (8,575.35 km) |
| Brussels to Sparks (Nevada) | 5,334.66 mi (8,585.30 km) |
| Brussels to Spartanburg (South Carolina) | 4,246.49 mi (6,834.07 km) |
| Brussels to Spearfish (South Dakota) | 4,576.35 mi (7,364.92 km) |
| Brussels to Speedway (Indiana) | 4,185.58 mi (6,736.04 km) |
| Brussels to Spencer (Iowa) | 4,351.80 mi (7,003.54 km) |
| Brussels to Spokane (Washington) | 4,805.90 mi (7,734.35 km) |
| Brussels to Spokane Valley (Washington) | 4,800.86 mi (7,726.24 km) |
