| Brookings to Olympia Heights (Florida) | 1,578.95 mi (2,541.08 km) |
| Brookings to Omaha (Nebraska) | 213.27 mi (343.23 km) |
| Brookings to On Top of the World Designated Place (Florida) | 1,317.64 mi (2,120.53 km) |
| Brookings to Onalaska (Wisconsin) | 278.23 mi (447.76 km) |
| Brookings to Oneida (New York) | 1,055.81 mi (1,699.17 km) |
| Brookings to Oneonta (New York) | 1,094.91 mi (1,762.09 km) |
| Brookings to Ontario (California) | 1,315.74 mi (2,117.48 km) |
| Brookings to Ontario (Oregon) | 998.35 mi (1,606.69 km) |
| Brookings to Opa-locka (Florida) | 1,571.34 mi (2,528.83 km) |
| Brookings to Opelika (Alabama) | 1,011.64 mi (1,628.08 km) |
| Brookings to Opelousas (Louisiana) | 985.83 mi (1,586.54 km) |
| Brookings to Orange (California) | 1,335.57 mi (2,149.40 km) |
| Brookings to Orange (Texas) | 993.56 mi (1,598.98 km) |
| Brookings to Orange City (Florida) | 1,361.10 mi (2,190.49 km) |
| Brookings to Orangeburg (South Carolina) | 1,132.36 mi (1,822.36 km) |
