| Boston to Scottsboro (Alabama) | 4,199.48 mi (6,758.41 km) |
| Boston to Scottsdale (Arizona) | 5,191.96 mi (8,355.66 km) |
| Boston to Scranton (Pennsylvania) | 3,469.02 mi (5,582.85 km) |
| Boston to Seabrook (Maryland) | 3,626.83 mi (5,836.82 km) |
| Boston to Seabrook (Texas) | 4,809.71 mi (7,740.48 km) |
| Boston to Seaford (New York) | 3,416.11 mi (5,497.69 km) |
| Boston to Seagoville (Texas) | 4,704.57 mi (7,571.27 km) |
| Boston to Seal Beach (California) | 5,388.27 mi (8,671.59 km) |
| Boston to Searcy (Arkansas) | 4,388.43 mi (7,062.50 km) |
| Boston to Seaside (California) | 5,333.84 mi (8,583.99 km) |
| Boston to SeaTac (Washington) | 4,715.40 mi (7,588.70 km) |
| Boston to Seattle (Washington) | 4,705.85 mi (7,573.33 km) |
| Boston to Sebastian (Florida) | 4,324.26 mi (6,959.23 km) |
| Boston to Sebring (Florida) | 4,379.64 mi (7,048.35 km) |
| Boston to Secaucus (New Jersey) | 3,433.84 mi (5,526.22 km) |
