| Boston to Enumclaw (Washington) | 4,721.46 mi (7,598.46 km) |
| Boston to Ephrata (Pennsylvania) | 3,544.89 mi (5,704.95 km) |
| Boston to Erie (Colorado) | 4,614.56 mi (7,426.42 km) |
| Boston to Erie (Pennsylvania) | 3,608.29 mi (5,806.99 km) |
| Boston to Erlanger (Kentucky) | 3,927.81 mi (6,321.21 km) |
| Boston to Escanaba (Michigan) | 3,703.81 mi (5,960.71 km) |
| Boston to Escondido (California) | 5,392.70 mi (8,678.70 km) |
| Boston to Española (New Mexico) | 4,867.52 mi (7,833.51 km) |
| Boston to Essex (Maryland) | 3,595.80 mi (5,786.88 km) |
| Boston to Essex Junction (Vermont) | 3,234.29 mi (5,205.09 km) |
| Boston to Estelle (Louisiana) | 4,604.11 mi (7,409.59 km) |
| Boston to Estero (Florida) | 4,447.87 mi (7,158.16 km) |
| Boston to Euclid (Ohio) | 3,688.02 mi (5,935.29 km) |
| Boston to Eufaula (Alabama) | 4,301.97 mi (6,923.35 km) |
| Boston to Eugene (Oregon) | 4,933.72 mi (7,940.06 km) |
