| Bluffton to Scottsboro (Alabama) | 339.45 mi (546.30 km) |
| Bluffton to Scottsdale (Arizona) | 1,789.71 mi (2,880.26 km) |
| Bluffton to Scranton (Pennsylvania) | 698.31 mi (1,123.82 km) |
| Bluffton to Seabrook (Maryland) | 520.58 mi (837.79 km) |
| Bluffton to Seabrook (Texas) | 854.47 mi (1,375.14 km) |
| Bluffton to Seaford (New York) | 715.05 mi (1,150.77 km) |
| Bluffton to Seagoville (Texas) | 910.23 mi (1,464.88 km) |
| Bluffton to Seal Beach (California) | 2,143.52 mi (3,449.67 km) |
| Bluffton to Searcy (Arkansas) | 654.69 mi (1,053.63 km) |
| Bluffton to Seaside (California) | 2,332.78 mi (3,754.24 km) |
| Bluffton to SeaTac (Washington) | 2,397.80 mi (3,858.89 km) |
| Bluffton to Seattle (Washington) | 2,401.30 mi (3,864.53 km) |
| Bluffton to Sebastian (Florida) | 307.35 mi (494.64 km) |
| Bluffton to Sebring (Florida) | 328.75 mi (529.07 km) |
| Bluffton to Secaucus (New Jersey) | 703.60 mi (1,132.34 km) |
