| Bluffton to Olympia Heights (Florida) | 449.81 mi (723.90 km) |
| Bluffton to Omaha (Nebraska) | 1,042.39 mi (1,677.56 km) |
| Bluffton to On Top of the World Designated Place (Florida) | 229.32 mi (369.05 km) |
| Bluffton to Onalaska (Wisconsin) | 979.73 mi (1,576.73 km) |
| Bluffton to Oneida (New York) | 803.60 mi (1,293.27 km) |
| Bluffton to Oneonta (New York) | 777.02 mi (1,250.49 km) |
| Bluffton to Ontario (California) | 2,114.57 mi (3,403.07 km) |
| Bluffton to Ontario (Oregon) | 2,101.62 mi (3,382.23 km) |
| Bluffton to Opa-locka (Florida) | 438.15 mi (705.13 km) |
| Bluffton to Opelika (Alabama) | 261.04 mi (420.10 km) |
| Bluffton to Opelousas (Louisiana) | 667.72 mi (1,074.59 km) |
| Bluffton to Orange (California) | 2,128.86 mi (3,426.07 km) |
| Bluffton to Orange (Texas) | 771.59 mi (1,241.75 km) |
| Bluffton to Orange City (Florida) | 227.53 mi (366.17 km) |
| Bluffton to Orangeburg (South Carolina) | 88.47 mi (142.38 km) |
