| Birmingham to Southern Pines (North Carolina) | 3,842.28 mi (6,183.55 km) |
| Birmingham to Southfield (Michigan) | 3,655.60 mi (5,883.11 km) |
| Birmingham to Southgate (Michigan) | 3,665.82 mi (5,899.57 km) |
| Birmingham to Southlake (Texas) | 4,655.13 mi (7,491.71 km) |
| Birmingham to Spanaway (Washington) | 4,716.14 mi (7,589.90 km) |
| Birmingham to Spanish Fork (Utah) | 4,787.30 mi (7,704.42 km) |
| Birmingham to Spanish Lake (Missouri) | 4,095.59 mi (6,591.21 km) |
| Birmingham to Spanish Springs (Nevada) | 5,063.01 mi (8,148.13 km) |
| Birmingham to Sparks (Nevada) | 5,069.16 mi (8,158.03 km) |
| Birmingham to Spartanburg (South Carolina) | 3,956.45 mi (6,367.30 km) |
| Birmingham to Spearfish (South Dakota) | 4,298.68 mi (6,918.06 km) |
| Birmingham to Speedway (Indiana) | 3,895.22 mi (6,268.75 km) |
| Birmingham to Spencer (Iowa) | 4,066.48 mi (6,544.37 km) |
| Birmingham to Spokane (Washington) | 4,547.94 mi (7,319.20 km) |
| Birmingham to Spokane Valley (Washington) | 4,542.62 mi (7,310.64 km) |
