| Big Spring to Eau Claire (Wisconsin) | 1,021.36 mi (1,643.72 km) |
| Big Spring to Echelon (New Jersey) | 1,563.20 mi (2,515.72 km) |
| Big Spring to Eden (North Carolina) | 1,271.27 mi (2,045.92 km) |
| Big Spring to Eden Prairie (Minnesota) | 971.92 mi (1,564.15 km) |
| Big Spring to Edgewater (Florida) | 1,240.33 mi (1,996.12 km) |
| Big Spring to Edgewater (New Jersey) | 1,629.78 mi (2,622.88 km) |
| Big Spring to Edgewood (Maryland) | 1,489.47 mi (2,397.07 km) |
| Big Spring to Edgewood (Washington) | 1,505.90 mi (2,423.52 km) |
| Big Spring to Edina (Minnesota) | 976.86 mi (1,572.10 km) |
| Big Spring to Edinburg (Texas) | 455.23 mi (732.62 km) |
| Big Spring to Edmond (Oklahoma) | 332.21 mi (534.65 km) |
| Big Spring to Edmonds (Washington) | 1,532.40 mi (2,466.16 km) |
| Big Spring to Edwards (Colorado) | 585.25 mi (941.88 km) |
| Big Spring to Edwardsville (Illinois) | 788.12 mi (1,268.35 km) |
| Big Spring to Effingham (Illinois) | 866.16 mi (1,393.95 km) |
