| Big Spring to Desert Hot Springs (California) | 879.09 mi (1,414.77 km) |
| Big Spring to DeSoto (Texas) | 270.39 mi (435.15 km) |
| Big Spring to Destin (Florida) | 894.33 mi (1,439.29 km) |
| Big Spring to Destrehan (Louisiana) | 675.62 mi (1,087.30 km) |
| Big Spring to Detroit (Michigan) | 1,225.01 mi (1,971.47 km) |
| Big Spring to Diamond Bar (California) | 952.10 mi (1,532.26 km) |
| Big Spring to Diamond Springs (California) | 1,174.16 mi (1,889.62 km) |
| Big Spring to Dickinson (North Dakota) | 1,014.79 mi (1,633.14 km) |
| Big Spring to Dickinson (Texas) | 426.59 mi (686.54 km) |
| Big Spring to Dickson (Tennessee) | 848.20 mi (1,365.05 km) |
| Big Spring to Difficult Run (Virginia) | 1,427.19 mi (2,296.83 km) |
| Big Spring to Dinuba (California) | 1,062.25 mi (1,709.53 km) |
| Big Spring to Discovery Bay (California) | 1,200.26 mi (1,931.63 km) |
| Big Spring to Dix Hills (New York) | 1,662.02 mi (2,674.76 km) |
| Big Spring to Dixon (California) | 1,221.02 mi (1,965.04 km) |
