| Big Spring to Delhi (California) | 1,149.12 mi (1,849.32 km) |
| Big Spring to Delray Beach (Florida) | 1,346.01 mi (2,166.20 km) |
| Big Spring to Deltona (Florida) | 1,225.46 mi (1,972.19 km) |
| Big Spring to Deming (New Mexico) | 366.48 mi (589.80 km) |
| Big Spring to Denison (Texas) | 302.84 mi (487.37 km) |
| Big Spring to Dent (Ohio) | 1,056.46 mi (1,700.21 km) |
| Big Spring to Denton (Texas) | 261.03 mi (420.09 km) |
| Big Spring to Dentsville (South Carolina) | 1,191.98 mi (1,918.31 km) |
| Big Spring to Denver (Colorado) | 553.25 mi (890.37 km) |
| Big Spring to Depew (New York) | 1,441.90 mi (2,320.52 km) |
| Big Spring to Derby (Connecticut) | 1,682.64 mi (2,707.96 km) |
| Big Spring to Derby (Kansas) | 438.44 mi (705.60 km) |
| Big Spring to Des Moines (Iowa) | 776.97 mi (1,250.41 km) |
| Big Spring to Des Moines (Washington) | 1,513.67 mi (2,436.01 km) |
| Big Spring to Des Plaines (Illinois) | 1,006.39 mi (1,619.64 km) |
