| St. Louis (Missouri) to Panama City | 639.95 mi (1,029.91 km) |
| Dallas (Texas) to Panama City | 681.44 mi (1,096.68 km) |
| Washington (District of Columbia) to Panama City | 774.03 mi (1,245.68 km) |
| Baltimore (Maryland) to Panama City | 809.02 mi (1,302.00 km) |
| Chicago (Illinois) to Panama City | 812.44 mi (1,307.50 km) |
| Detroit (Michigan) to Panama City | 853.13 mi (1,372.98 km) |
| Philadelphia (Pennsylvania) to Panama City | 898.23 mi (1,445.57 km) |
| Brooklyn (New York) to Panama City | 973.73 mi (1,567.07 km) |
| New York (New York) to Panama City | 976.79 mi (1,572.00 km) |
| Queens (New York) to Panama City | 984.25 mi (1,583.99 km) |
| Minneapolis (Minnesota) to Panama City | 1,101.83 mi (1,773.23 km) |
| Boston (Massachusetts) to Panama City | 1,160.83 mi (1,868.18 km) |
| Denver (Colorado) to Panama City | 1,271.50 mi (2,046.28 km) |
| Phoenix (Arizona) to Panama City | 1,567.05 mi (2,521.92 km) |
| Las Vegas (Nevada) to Panama City | 1,757.25 mi (2,828.02 km) |
| San Diego (California) to Panama City | 1,858.73 mi (2,991.34 km) |
| Riverside (California) to Panama City | 1,871.89 mi (3,012.52 km) |
| Los Angeles (California) to Panama City | 1,929.62 mi (3,105.42 km) |
| San Francisco (California) to Panama City | 2,159.77 mi (3,475.82 km) |
| Portland (Oregon) to Panama City | 2,254.55 mi (3,628.35 km) |
| Seattle (Washington) to Panama City | 2,281.28 mi (3,671.36 km) |
| Tampa (Florida) to Panama City | 243.92 mi (392.55 km) |
| Atlanta (Georgia) to Panama City | 255.69 mi (411.50 km) |
| Miami (Florida) to Panama City | 448.45 mi (721.71 km) |
| Houston (Texas) to Panama City | 586.25 mi (943.48 km) |
