| Ashtabula to Olympia Heights (Florida) | 1,116.61 mi (1,797.01 km) |
| Ashtabula to Omaha (Nebraska) | 788.63 mi (1,269.17 km) |
| Ashtabula to On Top of the World Designated Place (Florida) | 886.57 mi (1,426.79 km) |
| Ashtabula to Onalaska (Wisconsin) | 544.51 mi (876.31 km) |
| Ashtabula to Oneida (New York) | 274.42 mi (441.64 km) |
| Ashtabula to Oneonta (New York) | 296.14 mi (476.60 km) |
| Ashtabula to Ontario (California) | 2,059.85 mi (3,315.00 km) |
| Ashtabula to Ontario (Oregon) | 1,820.78 mi (2,930.26 km) |
| Ashtabula to Opa-locka (Florida) | 1,104.60 mi (1,777.68 km) |
| Ashtabula to Opelika (Alabama) | 684.65 mi (1,101.84 km) |
| Ashtabula to Opelousas (Louisiana) | 1,003.73 mi (1,615.34 km) |
| Ashtabula to Orange (California) | 2,078.14 mi (3,344.44 km) |
| Ashtabula to Orange (Texas) | 1,086.00 mi (1,747.75 km) |
| Ashtabula to Orange City (Florida) | 894.88 mi (1,440.17 km) |
| Ashtabula to Orangeburg (South Carolina) | 579.55 mi (932.69 km) |
