| Asheville to Oswego (Illinois) | 524.91 mi (844.76 km) |
| Asheville to Oswego (New York) | 632.52 mi (1,017.94 km) |
| Asheville to Otsego (Minnesota) | 885.77 mi (1,425.51 km) |
| Asheville to Ottawa (Illinois) | 524.00 mi (843.30 km) |
| Asheville to Ottawa (Kansas) | 730.43 mi (1,175.51 km) |
| Asheville to Ottumwa (Iowa) | 653.45 mi (1,051.63 km) |
| Asheville to Overland (Missouri) | 481.39 mi (774.72 km) |
| Asheville to Overland Park (Kansas) | 705.06 mi (1,134.68 km) |
| Asheville to Overlea (Maryland) | 422.05 mi (679.22 km) |
| Asheville to Oviedo (Florida) | 484.25 mi (779.33 km) |
| Asheville to Owasso (Oklahoma) | 743.91 mi (1,197.20 km) |
| Asheville to Owatonna (Minnesota) | 815.68 mi (1,312.71 km) |
| Asheville to Owensboro (Kentucky) | 294.56 mi (474.05 km) |
| Asheville to Owings Mills (Maryland) | 412.41 mi (663.72 km) |
| Asheville to Owosso (Michigan) | 520.26 mi (837.27 km) |
