| Asheville to Olympia Heights (Florida) | 692.90 mi (1,115.11 km) |
| Asheville to Omaha (Nebraska) | 828.55 mi (1,333.42 km) |
| Asheville to On Top of the World Designated Place (Florida) | 446.95 mi (719.30 km) |
| Asheville to Onalaska (Wisconsin) | 735.13 mi (1,183.08 km) |
| Asheville to Oneida (New York) | 635.61 mi (1,022.92 km) |
| Asheville to Oneonta (New York) | 622.22 mi (1,001.36 km) |
| Asheville to Ontario (California) | 1,980.96 mi (3,188.05 km) |
| Asheville to Ontario (Oregon) | 1,902.56 mi (3,061.88 km) |
| Asheville to Opa-locka (Florida) | 681.94 mi (1,097.47 km) |
| Asheville to Opelika (Alabama) | 257.83 mi (414.94 km) |
| Asheville to Opelousas (Louisiana) | 652.20 mi (1,049.62 km) |
| Asheville to Orange (California) | 1,996.74 mi (3,213.45 km) |
| Asheville to Orange (Texas) | 750.85 mi (1,208.38 km) |
| Asheville to Orange City (Florida) | 464.41 mi (747.39 km) |
| Asheville to Orangeburg (South Carolina) | 172.70 mi (277.94 km) |
