| Asheville to Enumclaw (Washington) | 2,168.78 mi (3,490.31 km) |
| Asheville to Ephrata (Pennsylvania) | 471.20 mi (758.32 km) |
| Asheville to Erie (Colorado) | 1,262.03 mi (2,031.05 km) |
| Asheville to Erie (Pennsylvania) | 471.51 mi (758.82 km) |
| Asheville to Erlanger (Kentucky) | 262.63 mi (422.66 km) |
| Asheville to Escanaba (Michigan) | 741.94 mi (1,194.04 km) |
| Asheville to Escondido (California) | 1,966.16 mi (3,164.23 km) |
| Asheville to Española (New Mexico) | 1,315.10 mi (2,116.44 km) |
| Asheville to Essex (Maryland) | 422.66 mi (680.20 km) |
| Asheville to Essex Junction (Vermont) | 792.08 mi (1,274.73 km) |
| Asheville to Estelle (Louisiana) | 590.48 mi (950.29 km) |
| Asheville to Estero (Florida) | 633.32 mi (1,019.22 km) |
| Asheville to Euclid (Ohio) | 419.64 mi (675.35 km) |
| Asheville to Eufaula (Alabama) | 293.61 mi (472.52 km) |
| Asheville to Eugene (Oregon) | 2,207.05 mi (3,551.90 km) |
