| Asheboro to Southern Pines (North Carolina) | 42.84 mi (68.95 km) |
| Asheboro to Southfield (Michigan) | 502.25 mi (808.30 km) |
| Asheboro to Southgate (Michigan) | 483.87 mi (778.71 km) |
| Asheboro to Southlake (Texas) | 1,006.00 mi (1,619.00 km) |
| Asheboro to Spanaway (Washington) | 2,310.93 mi (3,719.08 km) |
| Asheboro to Spanish Fork (Utah) | 1,751.69 mi (2,819.08 km) |
| Asheboro to Spanish Lake (Missouri) | 609.39 mi (980.72 km) |
| Asheboro to Spanish Springs (Nevada) | 2,178.28 mi (3,505.60 km) |
| Asheboro to Sparks (Nevada) | 2,181.33 mi (3,510.51 km) |
| Asheboro to Spartanburg (South Carolina) | 130.46 mi (209.95 km) |
| Asheboro to Spearfish (South Dakota) | 1,398.93 mi (2,251.37 km) |
| Asheboro to Speedway (Indiana) | 450.31 mi (724.71 km) |
| Asheboro to Spencer (Iowa) | 964.05 mi (1,551.48 km) |
| Asheboro to Spokane (Washington) | 2,083.79 mi (3,353.53 km) |
| Asheboro to Spokane Valley (Washington) | 2,074.63 mi (3,338.80 km) |
