| Appleton to St. George (Utah) | 4,959.06 mi (7,980.84 km) |
| Appleton to St. Helens (Oregon) | 4,734.30 mi (7,619.12 km) |
| Appleton to St. James (New York) | 3,285.59 mi (5,287.65 km) |
| Appleton to St. John (Indiana) | 3,814.49 mi (6,138.83 km) |
| Appleton to St. Joseph (Missouri) | 4,168.87 mi (6,709.15 km) |
| Appleton to St. Louis (Missouri) | 4,055.22 mi (6,526.25 km) |
| Appleton to St. Louis Park (Minnesota) | 3,861.75 mi (6,214.89 km) |
| Appleton to St. Marys (Georgia) | 4,109.28 mi (6,613.25 km) |
| Appleton to St. Marys (Pennsylvania) | 3,471.74 mi (5,587.23 km) |
| Appleton to St. Matthews (Kentucky) | 3,898.43 mi (6,273.92 km) |
| Appleton to St. Michael (Minnesota) | 3,861.16 mi (6,213.94 km) |
| Appleton to St. Paul (Minnesota) | 3,852.59 mi (6,200.15 km) |
| Appleton to St. Peter (Minnesota) | 3,912.75 mi (6,296.97 km) |
| Appleton to St. Peters (Missouri) | 4,061.55 mi (6,536.43 km) |
| Appleton to St. Petersburg (Florida) | 4,305.17 mi (6,928.50 km) |
