| Appleton to Smyrna (Delaware) | 3,455.31 mi (5,560.78 km) |
| Appleton to Smyrna (Georgia) | 4,070.81 mi (6,551.33 km) |
| Appleton to Smyrna (Tennessee) | 4,044.85 mi (6,509.56 km) |
| Appleton to Snellville (Georgia) | 4,050.83 mi (6,519.18 km) |
| Appleton to Snoqualmie (Washington) | 4,612.71 mi (7,423.44 km) |
| Appleton to Snyder (Texas) | 4,758.36 mi (7,657.84 km) |
| Appleton to Socastee (South Carolina) | 3,859.39 mi (6,211.09 km) |
| Appleton to Socorro (Texas) | 5,010.72 mi (8,063.98 km) |
| Appleton to Soddy-Daisy (Tennessee) | 4,027.29 mi (6,481.30 km) |
| Appleton to Solana Beach (California) | 5,309.46 mi (8,544.75 km) |
| Appleton to Soledad (California) | 5,237.43 mi (8,428.82 km) |
| Appleton to Solon (Ohio) | 3,587.71 mi (5,773.87 km) |
| Appleton to Somers Point (New Jersey) | 3,414.26 mi (5,494.72 km) |
| Appleton to Somerset (Kentucky) | 3,915.35 mi (6,301.15 km) |
| Appleton to Somerset (New Jersey) | 3,355.82 mi (5,400.66 km) |
