| Appleton to Security-Widefield (Colorado) | 4,571.88 mi (7,357.74 km) |
| Appleton to Sedalia (Missouri) | 4,163.44 mi (6,700.41 km) |
| Appleton to Sedro-Woolley (Washington) | 4,567.06 mi (7,349.98 km) |
| Appleton to Seguin (Texas) | 4,815.12 mi (7,749.18 km) |
| Appleton to Selden (New York) | 3,281.60 mi (5,281.22 km) |
| Appleton to Selma (Alabama) | 4,243.28 mi (6,828.90 km) |
| Appleton to Selma (California) | 5,177.68 mi (8,332.67 km) |
| Appleton to Selma (Texas) | 4,828.39 mi (7,770.55 km) |
| Appleton to Seminole (Florida) | 4,307.39 mi (6,932.07 km) |
| Appleton to Seven Hills (Ohio) | 3,597.01 mi (5,788.82 km) |
| Appleton to Seven Oaks (South Carolina) | 3,927.36 mi (6,320.47 km) |
| Appleton to Severn (Maryland) | 3,505.88 mi (5,642.18 km) |
| Appleton to Severna Park (Maryland) | 3,503.09 mi (5,637.67 km) |
| Appleton to Sevierville (Tennessee) | 3,933.03 mi (6,329.60 km) |
| Appleton to Seymour (Indiana) | 3,874.34 mi (6,235.15 km) |
