| Appleton to Sanford (Maine) | 3,079.41 mi (4,955.83 km) |
| Appleton to Sanford (North Carolina) | 3,778.11 mi (6,080.28 km) |
| Appleton to Sanger (California) | 5,168.59 mi (8,318.05 km) |
| Appleton to Santa Ana (California) | 5,286.85 mi (8,508.36 km) |
| Appleton to Santa Barbara (California) | 5,304.81 mi (8,537.26 km) |
| Appleton to Santa Clara (California) | 5,202.39 mi (8,372.44 km) |
| Appleton to Santa Clara (Oregon) | 4,843.34 mi (7,794.61 km) |
| Appleton to Santa Clarita (California) | 5,267.15 mi (8,476.65 km) |
| Appleton to Santa Cruz (California) | 5,226.84 mi (8,411.79 km) |
| Appleton to Santa Fe (New Mexico) | 4,781.53 mi (7,695.14 km) |
| Appleton to Santa Fe (Texas) | 4,715.76 mi (7,589.29 km) |
| Appleton to Santa Fe Springs (California) | 5,281.31 mi (8,499.45 km) |
| Appleton to Santa Maria (California) | 5,297.87 mi (8,526.10 km) |
| Appleton to Santa Monica (California) | 5,289.36 mi (8,512.40 km) |
| Appleton to Santa Paula (California) | 5,288.66 mi (8,511.28 km) |
