| Appleton to San Luis Obispo (California) | 5,285.42 mi (8,506.06 km) |
| Appleton to San Marcos (California) | 5,298.70 mi (8,527.44 km) |
| Appleton to San Marcos (Texas) | 4,798.71 mi (7,722.78 km) |
| Appleton to San Marino (California) | 5,272.02 mi (8,484.50 km) |
| Appleton to San Mateo (California) | 5,201.58 mi (8,371.14 km) |
| Appleton to San Pablo (California) | 5,178.52 mi (8,334.02 km) |
| Appleton to San Rafael (California) | 5,182.15 mi (8,339.86 km) |
| Appleton to San Ramon (California) | 5,178.30 mi (8,333.66 km) |
| Appleton to San Tan Valley (Arizona) | 5,110.37 mi (8,224.34 km) |
| Appleton to Sand Springs (Oklahoma) | 4,401.66 mi (7,083.79 km) |
| Appleton to Sandusky (Ohio) | 3,633.48 mi (5,847.51 km) |
| Appleton to Sandy (Oregon) | 4,745.97 mi (7,637.91 km) |
| Appleton to Sandy (Utah) | 4,709.89 mi (7,579.84 km) |
| Appleton to Sandy Springs (Georgia) | 4,061.34 mi (6,536.10 km) |
| Appleton to Sanford (Florida) | 4,197.50 mi (6,755.23 km) |
