| Appleton to Odessa (Texas) | 4,855.76 mi (7,814.59 km) |
| Appleton to Ogden (Utah) | 4,677.57 mi (7,527.82 km) |
| Appleton to Oildale (California) | 5,225.56 mi (8,409.73 km) |
| Appleton to Ojus (Florida) | 4,298.19 mi (6,917.27 km) |
| Appleton to Okemos (Michigan) | 3,640.23 mi (5,858.39 km) |
| Appleton to Oklahoma City (Oklahoma) | 4,487.57 mi (7,222.04 km) |
| Appleton to Okmulgee (Oklahoma) | 4,424.12 mi (7,119.93 km) |
| Appleton to Olathe (Kansas) | 4,213.00 mi (6,780.16 km) |
| Appleton to Old Jamestown (Missouri) | 4,046.65 mi (6,512.46 km) |
| Appleton to Oldsmar (Florida) | 4,292.07 mi (6,907.41 km) |
| Appleton to Olean (New York) | 3,439.51 mi (5,535.36 km) |
| Appleton to Olive Branch (Mississippi) | 4,223.98 mi (6,797.84 km) |
| Appleton to Olivehurst (California) | 5,090.64 mi (8,192.60 km) |
| Appleton to Olney (Maryland) | 3,520.30 mi (5,665.38 km) |
| Appleton to Olympia (Washington) | 4,668.36 mi (7,512.99 km) |
