| Appleton to Medford (New York) | 3,281.38 mi (5,280.87 km) |
| Appleton to Medford (Oregon) | 4,938.67 mi (7,948.01 km) |
| Appleton to Medina (Ohio) | 3,615.88 mi (5,819.20 km) |
| Appleton to Medulla (Florida) | 4,269.15 mi (6,870.53 km) |
| Appleton to Mehlville (Missouri) | 4,064.49 mi (6,541.17 km) |
| Appleton to Melbourne (Florida) | 4,207.48 mi (6,771.28 km) |
| Appleton to Melissa (Texas) | 4,565.80 mi (7,347.94 km) |
| Appleton to Melrose (Massachusetts) | 3,132.83 mi (5,041.81 km) |
| Appleton to Melrose Park (Illinois) | 3,807.32 mi (6,127.28 km) |
| Appleton to Melville (New York) | 3,300.01 mi (5,310.86 km) |
| Appleton to Melvindale (Michigan) | 3,613.08 mi (5,814.69 km) |
| Appleton to Memphis (Florida) | 4,313.83 mi (6,942.44 km) |
| Appleton to Memphis (Tennessee) | 4,221.11 mi (6,793.21 km) |
| Appleton to Menasha (Wisconsin) | 3,719.30 mi (5,985.64 km) |
| Appleton to Mendota (California) | 5,190.25 mi (8,352.89 km) |
