| Appleton to Indianola (Iowa) | 4,043.34 mi (6,507.13 km) |
| Appleton to Indio (California) | 5,234.02 mi (8,423.34 km) |
| Appleton to Inglewood (California) | 5,288.89 mi (8,511.64 km) |
| Appleton to Inkster (Michigan) | 3,617.66 mi (5,822.06 km) |
| Appleton to Inver Grove Heights (Minnesota) | 3,856.92 mi (6,207.11 km) |
| Appleton to Inwood (New York) | 3,320.83 mi (5,344.36 km) |
| Appleton to Iona (Florida) | 4,342.64 mi (6,988.80 km) |
| Appleton to Ionia (Michigan) | 3,652.47 mi (5,878.08 km) |
| Appleton to Iowa City (Iowa) | 3,954.78 mi (6,364.60 km) |
| Appleton to Irmo (South Carolina) | 3,926.76 mi (6,319.51 km) |
| Appleton to Irondale (Alabama) | 4,171.46 mi (6,713.32 km) |
| Appleton to Ironton (Ohio) | 3,769.93 mi (6,067.11 km) |
| Appleton to Irvine (California) | 5,286.82 mi (8,508.31 km) |
| Appleton to Irving (Texas) | 4,603.95 mi (7,409.35 km) |
| Appleton to Isabela (Puerto Rico) | 4,152.63 mi (6,683.02 km) |
